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Oral Antibiotics for Step-Down Therapy in Uncomplicated Gram-Negative Bacteremia


 
 
                                                                                                               Seven days of antibiotics were as good as 14 for gram-negative bacteremia -  PulmCCM
 
 
 
Join Dr. Molly Jorns for this virtual home study presentation where she will review background information and current literature on step-down therapy to oral antibiotics in patients with gram-negative bacteremia. The presentation will begin by describing the epidemiology of and risk factors for gram-negative bacteremia. Next, common pathogens and principles of treatment will be reviewed, including several trials pertaining to seven versus fourteen days of antimicrobial therapy. Available literature pertaining to step-down in gram-negative bacteremia will be summarized followed by other pertinent retrospective case studies which include patients with bactermia due to a variety of sources. The presentation will then move into a review and analysis of a trial comparing fluoroquinolones to beta lactams as oral step-down agents as well as a large meta-analysis. The presentation will conclude with evaluation of how step-down to oral antibiotics fits into treatment algorithms for patients with gram-negative bacteremia. 
 
To learn more about this activity, including speaker information and learning objectives, expand the module below (click the +). Pharmacists can earn 0.75 contact hour of knowledge-based CE credit at the completion of this activity.
 
This session will be held in a virtual home study format. All pharmacists are welcome to attend! Alumni can receive a coupon code to participate in this program at no cost by emailing alumni@uhsp.edu to verify alumni status.

Fee

$8.00

CE Hours

0.75

Activity Type

  • Knowledge

Target Audience(s)

  • Pharmacists

Accreditation(s)

Accreditation Council for Pharmacy Education
St. Louis College of Pharmacy at the University of Health Sciences and Pharmacy in St. Louis is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. To learn more about the specific program information, including universal activity numbers (UAN's) and learning objectives, please expand the modules below. Following successful completion of an evaluation, CE credit will be automatically reported to NABP through the CPE Monitor system, using the NABP ePID numbers and date of birth (MMDD) stored in participants' user profiles. Follow this link to learn more about CPE Monitor and the credit reporting process »  Participants are responsible for ensuring receipt of credit; no credit can be corrected or awarded if more than 60 days have passed from the date of the event or if the home study is expired.
 
It is the policy of St. Louis College of Pharmacy at the University of Health Sciences and Pharmacy in St. Louis, to ensure balance, independence, objectivity and scientific rigor in all its educational programs. All faculty participating in this program are expected to disclose to the program audience any real or apparent conflicts of interest related to the content of the presentation.

Requirements for CE Credit

To claim credit for this session, participants must complete the following steps:
  1. Visit this site. Make sure you are logged in and registered before proceeding.
  2. Complete an evaluation by clicking the green evaluation button
  3. Enter the evaluation code that was given to you at the end of the session you attended.
  4. Answer all questions honestly - we appreciate your feedback! All responses are stored anonymously.
  5. Click submit. As soon as you submit, a report containing the NABP ePID and DOB stored in your profile will be automatically sent to CPE Monitor.
  6. Please allow up to 48 hours for processing. Your credit should appear in your NABP profile online.
If you experience difficulty, please contact our office so that we may assist you. We are happy to help!
 
Participants are responsible for ensuring accuracy of credit reporting and receipt of credit. It is recommended that participants log on and review the information under "my account" prior to submitting the evaluation. NABP ePID and date of birth must be accurate for credit reporting to occur. Evaluations cannot be reopened after 14 days.
 
Participants are encouraged to check their NABP e-profiles for receipt of credit within one week of submitting their evaluation(s). If a participant notices an error in credit on their NABP e-profile, they are encouraged to contact our office as soon as possible. To best comply with ACPE's CE credit reporting policy, the University of health Sciences and Pharmacy in St. Louis is unable, for any reason, to award or correct CE credit if more than 60 days have passed from the event.
 
Learn more! Click the + symbol to expand.
 

 

 

 

This continuing education seminar will examine the role of step-down therapy to oral antibiotics in patients with gram-negative bacteremia. The presentation will begin by describing the epidemiology of and risk factors for gram-negative bacteremia. Next, common pathogens and principles of treatment will be reviewed, including several trials pertaining to seven versus fourteen days of antimicrobial therapy. Available literature pertaining to step-down in gram-negative bacteremia will be summarized followed by other pertinent retrospective case studies which include patients with bactermia due to a variety of sources. The presentation will then move into a review and analysis of a trial comparing fluoroquinolones to beta lactams as oral step-down agents as well as a large meta-analysis. The presentation will conclude with evaluation of how step-down to oral antibiotics fits into treatment algorithms for patients with gram-negative bacteremia. 

Objectives

  • Identify common pathogens associated with gram-negative bacteremia
  • Distinguish between high, moderate, and low bioavailability antibiotics
  • Select patients who are candidates for oral antibiotic step-down therapy in uncomplicated gram-negative bacteremia

Speaker(s)/Author(s)

Molly Jorns, Pharm.D.

Activity Number

0033-0000-22-001-H01-P

Release Date: Jan 7, 2022
Credit Expiration Date: Jan 7, 2025

CE Hours

0.75

Fee

$8.00